PhD Projects

Our students are studying diverse areas of mechanistic biology in the following BBSRC strategic themes:

Advancing the frontiers of bioscience discovery:

1) Understanding the rules of life (formerly World Class Underpinning Bioscience)

2) Transformative technologies (formerly Exploiting New Ways of Working)

Tackling strategic challenges:

3) Bioscience for sustainable agriculture and food (formerly Agriculture and Food Security)

4) Bioscience for renewable resources and clean growth (formerly Industrial Biotechnology and Bioenergy)

These are the new BBSRC priority areas, taken from strategic document, “Forward look for UK Bioscience”, available on the BBSRC website:

https://bbsrc.ukri.org/documents/forward-look-for-uk-bioscience-pdf/

	Name	Project title
	Catherine Russell University of York 2018	Investigating Bromodomain Proteins as Targets for anti-Leishmanial Drug Discovery
	Amy Brown University of York 2018	The role of the stress kinase MLTK7 in muscle disease
	Liam Maddison University of Leeds 2018	Probing the function of RNA methylation through chemical biology (iCASE)
	Rachel Greenhill University of Sheffield 2018	Identification and functional validation of effector genes in the parasitic weed Striga asiatica
	Maria Nikolova University of Leeds 2018	Mechanism and structure of the PACE family of transport proteins
	Josh Lee University of York 2018	Probing the epitranscriptome with nanopore sequencing (iCASE)
	Alice Seleiro University of Sheffield 2018	Uncovering underlying cellular mechanisms at work under high cell density E. coli protein production conditions in biotechnology (iCASE)
	Evie Farnham University of York 2018	Evolution, virulence and dispersal of bacterial plant pathogen, Ralstonia solanacearum (iCASE)
	Amber Emmett University of Leeds 2018	Machine Learning to Predict Genetic Regulation in Blood Cells
	Adam Casey University of Leeds 2018	Improving pest management in coffee plantations (iCASE)
	Katie West University of York 2018	Understanding long non-­coding RNA function
	Savvas Ioannou University of York 2018	Engineering extracellular vesicles derived from human mesenchymal stem cells
	James Forsythe University of York 2018	How does the circadian clock regulate disease resistance?
	Ashley Hayes University of Leeds 2018	Investigating How Nematodes Manipulate the Plant Secretory Pathway
	John Armstrong University of York 2017	Borrowing building blocks from bacteria and eukaryotes: a three-component DNA segregation machinery in archaea
	Rachael Cooper University of York 2017	How do repetitive bacterial surface proteins avoid inter-domain aggregation?
	Rhianna Rowland University of York 2017	Imaging agents for genetic disease: structural, chemical and cellular dissection
	Sarah Tindall University of York 2017	Structural analysis of acyltransferase proteins involved in O-antigen modification
	Sarah Thorne University of York 2017	Improved wheat yield with silicon
	Kirstin Spence University of York 2017	Investigating the molecular machinery that controls autophagy during Leishmania spp. Differentiation
	Edward Nay University of York 2017	Regulation of gene expression in Leishmania parasites: structure, function and post-transcriptional modification of RNA binding proteins
	Jessica Dobson University of York 2017	Mechanisms of palladium uptake and nanoparticle formation by plants
	Grace Dobbs University of York 2017	Role of CIZ1 in X chromosome inactivation
	Grace Cowen University of York 2017	Role of DNA methylation in brain function
	Ana Almeida Jones University of Sheffield 2017	Ahead of the curve: imaging and computational analysis of shape and form in the developing zebrafish ear
	Amy Tooke University of Sheffield 2017	Seeing is believing, observing bacterial biofilm formation in vivo
	Emily Guest University of Sheffield 2017	Linking metabolomics and metagenomics to resolve plant-microbial interactions involved in soil aggregation
	Amber Shun-Shion University of Sheffield 2017	Elucidating the role of STX19 in tissue morphogenesis using advanced bioimaging
	Ben Stevenson University of Sheffield 2017	The Dystroglycan LINC
	Ash Griffin University of Sheffield 2017	Application of high-resolution phosphoproteomics to reveal novel metabolic control mechanisms in Campylobacter jejuni
	Stella Christou University of Sheffield 2017	Elucidating the role of Endocytosis in Candida survival and proliferation in host cells
	Ben Scales University of Sheffield 2017	Neural bases of honeybee visual information processing and locomotion control
	Daniel Green University of Sheffield 2017	Neural circuit mechanisms of adaptation or sensitisation to neonicotinoid insecticides
	Lorna Malone University of Sheffield 2017	Structural role of photosystem II supercomplexes in thylakoid membrane stacking
	Shauni McGregor University of Sheffield 2017	The Mechanics of Stomatal Function
	Sarah Stevenson (nee Gratton) University of Sheffield 2017	Generating distinct actin networks in a single cytoplasm: Structural studies to determine the impact of actin nucleators on filament structure
	Ivaylo Yonchev University of Sheffield 2017	How does DNA damage alter nuclear mRNA export in humans?
	Ankur Patel University of Sheffield 2017	CASE - Development of an automated, high-resolution analysis pipeline for bacterial peptidoglycan structural analyses
	Laurence de Lussy-Kubisa University of Sheffield 2017	CASE - High-throughput genetic analysis of a butanol-producing Clostridia
	Thomas Grand University of Sheffield 2017	CASE - The Mechanism of Cell Cycle Repression in Tubers
	Alice Thomas University of York 2017	More Sustainable Crop Production by Using Better Fertilisers (CASE)
	Oliver Noble University of York 2017	MCMs: a novel nanopore (CASE)
	Maria Markham University of York 2017	CASE - Cell Stress and How to Prevent It
	Luke Trask University of Leeds 2017	CASE - Probing the functions of NEK family kinases using allosteric inhibitors
	Jonathan Dolan University of Leeds 2017	CASE - Orthogonal ligation strategies for making well defined glycoconjugate vaccines
	Bethan Cole University of Leeds 2017	CASE - Function and pharmacology of human Na+-activated K+ channels
	Jessica Boakes University of Leeds 2017	CASE - Structural characterisation of the equilibrative nucleoside transporter, a cancer drug target
	Jenny Hayes University of York 2016	CASE - Metabolic oligosaccharide engineering (MOE) using Sortases
	Nicola Burns University of York 2016	CASE - Genetic and environmental effects on virulence of European foulbrood, a bacterial pathogen of honey bees
	Patrick Shire University of Sheffield 2016	CASE - Mechanisms of endosomal permeability and release: a route for enhancing cytoplasmic delivery of endocytosed therapeutics