PhD Projects

Our students are studying diverse areas of mechanistic biology in the following BBSRC strategic themes:

Advancing the frontiers of bioscience discovery:

1) Understanding the rules of life (formerly World Class Underpinning Bioscience)

2) Transformative technologies (formerly Exploiting New Ways of Working)

Tackling strategic challenges:

3) Bioscience for sustainable agriculture and food (formerly Agriculture and Food Security)

4) Bioscience for renewable resources and clean growth (formerly Industrial Biotechnology and Bioenergy)

These are the new BBSRC priority areas, taken from strategic document, “Forward look for UK Bioscience”, available on the BBSRC website:

https://bbsrc.ukri.org/documents/forward-look-for-uk-bioscience-pdf/

	Name	Project title
	Alina Capatina University of York 2019	Regulation of cellular metabolism and intercellular communication by sodium signalling
	Owen Laing University of Sheffield 2019	Molecular mechanisms underlying replicative stress and genome damage in pluripotent stem cells (i-CASE)
	Peter Daniels University of Sheffield 2019	Characterisation of the Rex1 ribonuclease in yeast and human cells
	Federica Pastorelli University of Sheffield 2019	1/ Characterization of cyclic electron flow around photosystem I in photosynthesis 2/ Super-resolution video rate imaging of photosynthetic membrane dynamics in plants and algae
	Megan Lovatt University of Leeds 2019	SSA Cryo-electron Tomography of Activated Mammalian Synapses
	Conor Scott University of York 2019	Mining the secretome of the lignocellulose degrading fungus Parascedosporium putredinis NO1 (i-CASE)
	Larra Trinidad University of Sheffield 2019	Epithelial morphogenesis: coordinating planar polarity and tissue mechanics
	Joseph Nabarro University of York 2019	Probing the dynamics, orientation and conformation of lipopolysaccharide in bacterial membranes through bio-orthogonal chemistry and single-molecule biophysics
	Jessica Davis University of Sheffield 2019	Structural characterization of the enterococcal polysaccharide antigen and analysis of its contribution to cell growth, division and antibiotic resistance
	Cara Wheeldon University of Leeds 2019	The role of root exudates in density-dependent growth responses in plants
	Quentin Levicky University of Sheffield 2019	Development of Debaryomyces hansenii as a robust host for production of high value fatty acid-based biochemicals.
	Katie Gelder University of Sheffield 2019	Investigating the role of phase separation in enhancer-dependent gene regulation
	Kyle Le Huray University of Leeds 2019	Investigation into the determinants of protein-lipid interactions using molecular dynamics simulations, machine learning and mass spectrometry
	Alexandra Holmes University of Leeds 2018	Investigating the Structure and Function of Membrane-Integral Pyrophosphatases
	Robert Brench University of Sheffield 2019	Speeding towards efficient stomata - the molecular mechanisms that underpin increased stomatal efficiency
	Hannah Jones University of York 2019	Seasonality control of barley flowering: from the lab to the field (i-CASE)
	Kathryn Billane University of Sheffield 2019	The evolution of multidrug resistant bacterial pathogens
	Jessica Edge University of Leeds 2019	MicroRNA evolution in placental mammals: Unravelling conservation and divergence in their regulatory mechanisms in early pregnancy in different placental mammals
	Kane Yoon University of Leeds 2019	Epigenetics, embryogenesis and plasticity in insects
	Thomas Hamer University of Sheffield 2019	Molecular localisation of Staphylococus aureus surface proteins
	Harry Schofield University of Leeds 2019	Structural and mechanistic insights into antibiotic resistance in Staphylococcus aureus
	Jessica Mcneill University of Sheffield 2019	Plasticity of clathrin-mediated endocytosis in development
	Rosalind Latham University of Leeds 2019	Nuclease-resistant DNA nanostructures for high precision plant genome engineering
	Joanna Greenman University of York 2019	SSA Mechanisms and functional consequences of platelet-macrophage cross-talk in type 2 immunity
	Emily Byrd University of Leeds 2019	Probing the Conformational Dynamics of α-Synuclein by Structural Mass Spectrometry
	Charlotte Stevenson University of Leeds 2019	Programming the subcellular localization of enzyme inhibitors
	James Barrett University of York 2019	Super resolution imaging of the algal pyrenoid
	Claire Smithson University of Leeds 2019	Epigenetic mechanisms underlying responses to environmental stress
	Liam Barratt University of York 2019	Future-proofing Our Food: Increasing Tolerance to Abiotic Stress in Hexaploid Bread Wheat Using Associative Transcriptomics
	Megan Clarke University of Leeds 2019	Primed for parasitism: pathogenic nematodes tailor their response to host plant exudates
	Sameh ElBadry University of Sheffield 2019	Characterisation of the mechanism of HIF mediated genoprotection in zebrafish
	Zoe Ingold University of York 2019	Engineering Carbon-carbon Bond Forming Enzymes from Plants for Applications in Industrial Biotechnology
	Ezra Herman University of York 2019	Unravelling evolutionary mechanisms of phage-bacteria interactions in spatially structured microbial communities
	Jessica Downing University of York 2018	Genomics-guided approaches to enzyme discovery in the extremophile Galdieria sulphuraria (i-CASE)
	Madeleine Inglis University of Leeds 2018	Flight Control in Birds
	Egle Beigaite University of York 2018	Characterising a novel candidate gene regulating ageing related atrophy in neurons
	Alexander Setchfield University of York 2018	Microbial degradation of agricultural residues as feed for black soldier fly larvae (iCASE)
	Sonam Sidhu University of York 2018	Dissecting molecular complexity in single living cells using state-of-the-art super-resolution microscopy and biophysical chemistry, one molecule at a time
	Laura Wiggins University of York 2018	Using machine learning to predict cell type and fate in heterogeneous populations (NPIF)
	Alexander Scott University of York 2018	How does low-temperature plasma damage the bacterial outer membrane?
	Alexander Russell University of York 2018	Dissecting a role for ZAK-beta in skeletal muscle development using genetics and embryology in zebrafish and Xenopus
	Benjamin Rowlinson University of York 2018	Unravelling the structural biology of the LIMD1 scaffold protein using novel NMR approaches
	Katie Greenin University of Sheffield 2018	Maintaining effective sensory coding in the face of inter-neuronal variation
	Lianne Gahan University of Sheffield 2018	A new mathematical framework for Aβ peptide assembly in Alzheimer’s disease
	Thomas Emrich-Mills University of Sheffield 2018	Developing de novo architectures of photosynthetic complexes for the control of photocurrent output from reaction centres.
	Molly Patterson University of Leeds 2018	Re-wiring epithelial homeostasis: Papillomavirus targeting of the Hippo signalling
	Jacob Leese University of Leeds 2018	Investigating the molecular mechanisms underpinning the arthropod segmentation clock
	Katherine Harper University of Leeds 2018	The role of circRNA dysregulation during KSHV infection
	Lewis Hancock University of Sheffield 2018	Modelling complexity and redundancy in actin polymerization
	Romany Mclure University of Leeds 2018	Identifying and modulating aggregation propensity in bio-pharmaceuticals (i-CASE)