Host | Primary Supervisor | Project title |
Bradford | Amalia Ruiz Estrada | Harnessing mechanotransduction using magnetic nanoactuators to elicit cellular responses |
Bradford | Jacobo Elies | Investigating molecular determinants of cellular fate driven by air pollutants |
Bradford | Karthic Swaminathan | Deciphering the molecular mechanisms of mechanosensing in stem cell homeostasis and differentiation. |
Bradford | Sneha Swaroop | Understanding the interplay between endogenous endocrine signalling molecules and exogenous mimetics in normal breast and stem cells: An advanced model system approach. |
Bradford | Stuart Dickens | Investigating perineuronal nets modulation as a mechanism underlying diet induced cognitive impairment |
Bradford | Vibhu Jha | Integrated computational and biochemical investigation of EGFR-mediated cell signaling |
Hull | André Voelzmann | How does cross play of DNA replication, packaging and innate immune response determine assembly efficiency of viral vectors for gene therapies? |
Hull | Darron Cullen | Nurture versus nature in locusts – can we control their swarming behaviour? |
Hull | Domino Joyce | Seeing the light: how the dynamic structure of rhodopsin enables deepwater vision. |
Hull | Graham Ferrier | Revolutionising Early Detection of Crop Pathogenesis using AI-based analysis of digital Imagery. |
Hull | Jen Bright | The functional consequences of intra- and interspecific variation in the material properties of bird bone |
Hull | Mat Hardman | Modulating the ageing skin microbiome with cold atmospheric plasma |
Hull | Mauro Adriel Rinaldi | Synthetic organelles for biofuel biomanufacturing from waste biomass |
Hull | Paul Hiebert | A Next-Generation 3D Skin Model for Insights into Healthy Aging |
Leeds | Ade Whitehouse | Virus modification of nuclear condensates: understanding their role during infection |
Leeds | Amanda Bretman | It’s getting hot in here: how heatwaves impact health and ageing |
Leeds | Andrew Macdonald | Mechanisms of long non-coding RNA function in the human papillomavirus life cycle in primary epithelial tissues |
Leeds | Antonio Calabrese | Overcoming host cell protein contamination in the preparation of biopharmaceuticals |
Leeds | Antreas Kalli | Understanding how force is sensed in cells by the Piezo2 mechanosensitive channel |
Leeds | Bruce Turnbull | Exploring Protein-Glycan Interactions with Fluorinated Carbohydrates |
Leeds | Charlie Scarff | Unravelling the mechanisms of cardiac myosin function in health and disease through molecular dynamic simulation and electron microscopy |
Leeds | Eszter Csibra | Building orthogonal ribosome control for engineering biology |
Leeds | Graham Askew | Unravelling the mechanical function of the leg muscles during running |
Leeds | Ioannis Delis | Multisensory decision-making in the developing and aging human brain |
Leeds | Joe Cockburn | The seminal fluid extracellular matrix: a new paradigm in reproductive biology? |
Leeds | Julie Aspden | Dissecting mechanisms of translational regulation by specialised ribosomes |
Leeds | Michelle Peckham | Making and breaking myosin filaments: How smooth muscle cells modulate their contractile behaviour. |
Leeds | Neil Ranson | Understanding protein aggregation in human pancreatic tissue |
Leeds | P. E. Urwin | Translating the chemical cross-talk between plants and root symbionts through application of novel microfluidics devices |
Leeds | Paul Beales | Dynamics of metabolically-active biomolecular condensates |
Leeds | Pete Watson | Investigating the structural optimisation of bone through computational biomechanical modelling |
Leeds | Ralf Richter | Superselective targeting of perineuronal nets in the brain |
Leeds | Richard Bayliss | Probing covalent mechanisms of regulation and inhibition in mitotic kinases |
Leeds | Robin Bon | In situ studies of localisation, structure and interactions of TRPC5 ion channels |
Leeds | Ryan Seipke | Eavesdropping on the molecular dialogue between a standalone cyclase and its cognate nonribosomal peptide synthetase |
Leeds | Scott Bowen | Piezo1 as a novel mechanosensor regulating skeletal muscle fatigue and adaptation to exercise |
Leeds | Simon Goodman | Novel biosensor technology for environmental surveillance of emerging infectious diseases |
Leeds | Takashi Ochi | Structural studies of DNA double-strand break repair in plants |
Leeds | Tom Bennett | Understanding the molecular and physiological basis for crop-weed interactions for sustainable agriculture |
Leeds | Viktor Lukacs | Characterisation of a novel molecular temperature receptor |
Leeds | Yuan Guo | Elucidating lectin receptor signalling balance in dendritic cell function modulation in health and disease |
Leeds Beckett | Angela Oates | Respired Microplastics: Unveiling Hidden Infection and Cellular Risks |
Leeds Beckett | Arya Gupta | Piggybacking off ion-channel inhibitors to enhance activity of clinically relevant antibiotics against staphylococci |
Leeds Beckett | Jaskaren Kohli | Ageing and Infection: Does RNA sensing play a key role? |
Leeds Beckett | Jessica Haigh | Do insulin-resistant cells provide a favourable hiding place for bacteria? |
Leeds Beckett | Matt Hindle | The functional, metabolic and molecular cortisol-induced reprogramming of platelets |
Leeds Beckett | Wayne Roberts | Evaluating Platelet Microparticles as Novel Regulators of Vascular Health (PULSE) |
Leeds Beckett | Zoe Kolokotroni | Drivers of Food Consumption: Circadian Rhythm and Sleep–Wake Alterations in Eating Behaviour, and Metabolism. |
Sheffield | Andrew Fleming | The functional role of the epidermis in stomatal function |
Sheffield | Andrew Hitchcock | Exploring the structure and dynamics of Complex I and ATP synthase in phototrophic bacteria |
Sheffield | Anestis Tsakiridis | Deciphering the role of biomechanical cues in embryonic cell fate decisions using human pluripotent stem cells |
Sheffield | Chris Cooney | Using Artificial Intelligence to Reveal the Signature of Development in Organismal Colour Pattern Designs |
Sheffield | Dan Bose | Unveiling the Secrets of Intrinsically Disordered Proteins in Gene Regulation |
Sheffield | Ellie Harrison | Predicting pathogen evolution: using experimental evolution to understand the impact of phage therapy on Clostridioides difficile |
Sheffield | Erin Cutts | Developing Imaging Solutions to Study the Dynamics of Human Condensin I |
Sheffield | Helen Matthews | The role of keratin networks in maintaining tissue epithelial tissue integrity |
Sheffield | Henry Roehl | Regulation of regeneration by TGFbeta and SFKs |
Sheffield | Ian Lidbury | Exploring bacteria-mycorrhizal fungi-plant interactions regulating nutrient exchange |
Sheffield | Ian Sudbery | The regulatory mechanisms of 3’ UTR introns in stem cell differentiation |
Sheffield | Ivana Barbaric | The impact of mechanical stress on the genome maintenance in pluripotent stem cells |
Sheffield | Iwan Evans | Mining white blood cell diversity to enhance phagocytosis |
Sheffield | Katie Field | Optimising wheat-fungal symbioses for enhanced nutrition and sustainability |
Sheffield | Lisa Smith | Signalling complexes and cell wall changes during plant reproduction |
Sheffield | Luke Dunning | Horizontal gene transfer and its role in crop adaptation and evolution |
Sheffield | Matt Johnson | Determining the role of FNR location in the photoprotection of photosystem I |
Sheffield | Matthew Newton | How does non-coding RNA structure regulate gene expression? |
Sheffield | Matthew Towers | Investigating a polarity switch in bird wing feather development |
Sheffield | Mike Williamson | Deciphering the mechanism of Plasmodium apicoplast lagging strand replication |
Sheffield | Mirre Simons | Mechanisms of alternative splicing in neurodegeneration and ageing |
Sheffield | Nadav Amdursky | Deciphering proton shuttling on the surface of biological membranes toward proton translocating channels |
Sheffield | Nicola Nadeau | The genetic and developmental control of complex nanostructure formation in butterfly wing scales |
Sheffield | Per Bullough | Mechanism of phage infection in the C. difficile pathogen- towards effective phage therapy |
Sheffield | Sam Amsbury | Primed for Protection: Cell Wall Modifications in Plant Defense and Long-Term Immunity |
Sheffield | Sam Caton | Biological drivers of health inequalities: impact of diet on the gut microbiome in preschool children. |
Sheffield | Stuart Wilson | Understanding the structure of mRNA in vivo |
Sheffield | Tim Craggs | Predicting the structural ensembles of Intrinsically Disordered regions of proteins: The “alpha-fold” for IDRs |
Sheffield Hallam | Alexandra Males | Exploring enzyme-mediated degradation of plant biomass by in situ imaging for biosecurity |
Sheffield Hallam | Neil Cross | Multimodal mass spectrometry imaging to visualise the glycomic and metabolomic landscape for prostate cancer metastasis to bone |
Sheffield Hallam | Nick Peake | Extracellular vesicles and the microbiome: from top to bottom |
Sheffield Hallam | Nik Georgopoulos | Use of physiologically relevant in vitro cell models for the development of biology-driven approaches to enhance the efficacy of scalp and limb cooling technologies |
Sheffield Hallam | Simona Francese | Non-invasive detection of breast cancer from fingertip smears |
Teesside | Caroline Orr | OptiPol – Optimised composting of poultry manure for sustainable processing of farm waste |
Teesside | Claudio Angione | Transformer-Bio: integrating imaging and omics in large-scale food fermentation |
Teesside | Jamie Bojko | Nudivirus infection capacity across crustaceans of economic importance |
Teesside | Kalesh Karunakaran | Decoding the Cross-talk Between RNA-binding Proteins, Phosphorylation, and Molecular Chaperones in Post-Transcriptional Gene Regulation in Toxoplasma gondii. |
Teesside | Mohammad Dadashipour | Engineering Biocatalysis: Unleashing the Potential of Hyper-Thermostable Phosphorylated-Sugar Nucleotide Metabolising Enzymes |
Teesside | Omar Aboelazayem | Intensified biochemical and hydrothermal biorefinery for lignocellulosic biomass valorisation: A circular economy approach (BioTherm) |
York | Alan Cartmell | Host glycan metabolism underpins cross-phylum food webs in the human gut microbiota |
York | Andrea Harper | Chemical warfare in the rhizosphere: unpicking the defensive role of plant root exudates against the bacterial pathogen Ralstonia solanacearum |
York | Andrew Holding | Elucidating the Mechanism of Hypoxic Reprogramming of the Estrogen Response. |
York | Benjamin Lichman | Nature’s chemist: how a plant can produce the complex and diverse Daphniphyllum alkaloids |
York | Chris MacDonald | Understanding evolutionarily conserved mechanisms of membrane remodelling required for photosynthesis |
York | Christoph Baumann | Super-size them bugs: Engineering a stable, elongated bacterial strain for biomanufacturing. |
York | Daniel Ungar | Structural characterization of vesicle tethering at the Golgi |
York | Daniela Barillà | Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea |
York | Daphne Ezer | AI for adaptive gene networks over plant evolution |
York | Federico Sabbadin | Developing novel insecticidal proteins for crop protection |
York | Gavin Thomas | Understanding nickel homeostasis for improved industrial enzyme production |
York | Gavin Wright | Structural vaccinology to improve vaccine design for the parasitic livestock disease animal African trypanosomiasis. |
York | Gideon Grogan | Broadening the Catalytic Promiscuity of Amide Bond Synthetases using Directed Evolution and Robotic Screening |
York | Han-Jou Chen | Characterisation of the HSF1 regulatory complex |
York | Ioannis Kourtzelis | Unravelling the role of extracellular vesicles in the orchestration of macrophage – mediated immune regulation. |
York | Jamie Wood | Refinement of a computational model of glycan processing and its application to datasets of medical and biotechnological relevance |
York | Joana Faria | Making sense of antigenic variation in trypanosomes: a nuclear factory with a switching problem… |
York | Kanchon Dasmahapatra | Genetic and developmental basis of transparency in butterflies |
York | Katherine Denby | Genomics and genetics of traditional smallholder crops: amaranth and cowpea |
York | Liz Rylott | Developing plant-based solutions to recover technology-critical rare earth elements from wastes |
York | Luke Alphey | Understanding the role of piRNAs in mosquito immunity |
York | Martin Fascione | The sweet side of ‘evil twin’ sugars: using chemical glycobiology tools to explore the role bacterial sialic acids play in host immune evasion by pathogens |
York | Michael Plevin | Accelerating protein library screening via innovative sensor arrays |
York | Michelle Hawkins | How do helicases prevent replication and transcription machinery collisions? |
York | Pegine Walrad | Investigating the impact of PRMT-catalysed methylation on RBP:RNA interactions, mRNP granule formation (LLPS), structural dynamics and gene regulation |
York | Purba Mukherjee | Mechanistic study of the assembly and repair of unique bacterial telomeres in Streptomyces |
York | Sean Meaden | A Farewell to Arms: The Trade-off Between Growth and Defence in Bacteria |
York | Thierry Tonon | Why diatoms produce palmitvaccenic acid? |
York | Will Brackenbury | Bioelectrical control of epithelial cell behaviour |