PhD Projects

Our students are studying diverse areas of mechanistic biology in the following BBSRC strategic themes:

Advancing the frontiers of bioscience discovery:

1) Understanding the rules of life (formerly World Class Underpinning Bioscience)

2) Transformative technologies (formerly Exploiting New Ways of Working)

Tackling strategic challenges:

3) Bioscience for sustainable agriculture and food (formerly Agriculture and Food Security)

4) Bioscience for renewable resources and clean growth (formerly Industrial Biotechnology and Bioenergy)

These are the new BBSRC priority areas, taken from strategic document, “Forward look for UK Bioscience”, available on the BBSRC website:

https://bbsrc.ukri.org/documents/forward-look-for-uk-bioscience-pdf/

	Name	Project title
	Nicola Burns University of York 2016	CASE - Genetic and environmental effects on virulence of European foulbrood, a bacterial pathogen of honey bees
	Patrick Shire University of Sheffield 2016	CASE - Mechanisms of endosomal permeability and release: a route for enhancing cytoplasmic delivery of endocytosed therapeutics
	Naomi Cox University of Sheffield 2016	CASE - Engineering the rice leaf for improved photosynthesis
	Oliver Carnell University of Sheffield 2016	CASE - Functional analysis of a novel, essential vaccine component of Staphylococcus aureus
	Rachel Taylor University of Leeds 2017	CASE - Characterization of WHIRLY1 functions in cereal crops
	Jess Ebo University of Leeds 2016	CASE - Evolving and improving protein stability for enhanced biopharmaceuticals
	Ioannis Tsagakis University of Leeds 2017	Dissecting the molecular mechanisms of lncRNA function in X chromosome inactivation across mammalian gestation evolution
	Danielle Pierce University of Leeds 2017	Understanding foot-and-mouth disease virus (FMDV) replication
	Jack Wright University of Leeds 2017	Structural and mechanistic insights into ABC transporters
	Hayley Pearson University of Leeds 2017	Understanding the Role of Cellular Chloride Channels in Virus Induced Cancers
	Adam Binns University of Leeds 2017	The molecular basis of primary root and shoot gravitropism
	Jumana Akhtar University of Leeds 2017	Nutrient impacts on plant secretions into soil
	Louise Richardson University of Leeds 2017	The Role of Satellite Cells in Skeletal Muscle Plasticity
	Holly Morgan University of Leeds 2017	Investigating enzymatic methods for preparation of protein conjugates
	Sophie Meredith University of Leeds 2017	Biophysics of lipid membrane disruption induced by endotoxin (lipopolysaccharides)
	Siu Yi Lee University of Leeds 2017	Functional analysis of a novel viral RNA binding protein
	Maia Harvey University of Leeds 2017	Developing an in vivo platform to assess inhibitors of protein-protein interactions
	Becky Foster University of Leeds 2017	microRNA regulation of virus gene expression
	Chris Arter University of Leeds 2017	Activity-directed discovery of ATP-competitive probes of Nek7 kinase biology
	Alexander Bruce University of Leeds 2017	Understanding the role of protein mechanical strength in biofilm function and formation
	Manuela Lovinella University of York 2016	Developing a 3rd-generation genome pipeline to uncover novel metabolic activities in Galdieria: a focus on secreted enzyme activities
	Nick Yates University of York 2016	Bio-orthogonal conjugation for "wiring" redox-active proteins/enzymes to any conducting surface
	Lewis White University of York 2016	Life in extreme environments: adaptation and evolution of African soda lake fishes
	Andrew Stone University of York 2016	Defining the stem cell subtypes controlling bone and blood formation
	James Ronald University of York 2016	Setting a circadian clock: Structural understanding of the ligand-activation model of the circadian evening complex components ELF4 to ELF3
	Alastair Pizzey University of York 2016	The role of neural specific Src splice variants in neuronal specification and differentiation
	Oliver Herd University of York 2016	The roles of bone marrow stromal-derived thrombopoietin in HSC niche self-renewal
	Liam Chapman University of York 2016	Enhancing biofuel production through synthetic protein fusions
	Paul Bond University of York 2016	Next generation computer software for placing atoms in electron density maps
	Thomas Burns University of Sheffield 2016	Exploiting the value of the extremophile red alga Galdieria for Industrial Biotechnological benefits: White Rose BBSRC DTP Studentship Network in Industrial Biotechnology & Bioenergy
	Robert Smith University of Sheffield 2016	Functional analysis of a novel peptidoglycan binding domain conserved in Gram-positive nosocomial pathogens
	Kirsty Smitten University of Sheffield 2016	Antibacterial theranostics based on luminescent metal complexes
	Lukas Jasaitis University of Sheffield 2016	Self-assembled magnetic nanoparticle arrays: Rod-like scaffold proteins to precisely template the spatial organization of biomineralisation proteins.
	Harry Wood University of Sheffield 2016	The role of non active-site residues in enzyme catalysis
	Adam Brooks University of Sheffield 2016	Mechanistic studies of bacterial chromosome segregation using single-molecule microscopy
	Ainhao Dafis-Sagermendi University of Sheffield 2016	Electron cryo-microscopy (cryoEM) of sub-cellular assemblies
	Magdelena Dabrowska University of Sheffield 2016	Light regulation of gene expression and inter-tissue signaling
	Sarah Carroll University of Sheffield 2016	Shifting Shape with Cell Walls: Imaging the Dynamics of Guard Cell Movement
	Sarah Flannery University of Sheffield 2016	Role of nanodomains in compartmentalisation of electron transport functions in plant photosynthetic membranes.
	Peter Walker University of Sheffield 2016	Killing bacterial pathogens with blue light
	Matthew Hughes University of Leeds 2016	Harnessing the potential of extremophilic proteins from Galdieria through mechanistic insights into their stability and aggregation propensity
	Alexander Wright University of Leeds 2016	Exploiting extremophilic proteins as robust biological components for advanced biomaterials
	Emily Turri University of Leeds 2016	A synthetic biology approach to the production of terpenoids by pathway engineering.
	Amelia Shaw University of Leeds 2016	Arenavirus RNPs and Specialized Ribosomes
	Oliver Prosser University of Leeds 2016	Analysis and inhibition of chikungunya virus replication
	Philip Kirk University of Leeds 2016	Unlocking intercellular channels from cell wall biology to biophysics
	Tomasz Kaminski University of Leeds 2016	The rainbow cell – enabling technologies for immunofluorescence of living cells
	Marcus Holt University of Leeds 2016	Understanding the structure and function of ASPM, a protein essential for normal mitosis.
	James Henderson University of Leeds 2016	Towards a crystal structure of the Family B GPCR PTH2
	Sarah Good University of Leeds 2016	Understanding and Controlling Protein Aggregation and Disease: Molecular Mechanisms in vitro and in vivo