PhD Projects

Our students are studying diverse areas of mechanistic biology in the following BBSRC strategic themes:

Advancing the frontiers of bioscience discovery:

1) Understanding the rules of life (formerly World Class Underpinning Bioscience)

2) Transformative technologies (formerly Exploiting New Ways of Working)

Tackling strategic challenges:

3) Bioscience for sustainable agriculture and food (formerly Agriculture and Food Security)

4) Bioscience for renewable resources and clean growth (formerly Industrial Biotechnology and Bioenergy)

These are the new BBSRC priority areas, taken from strategic document, “Forward look for UK Bioscience”, available on the BBSRC website:

https://bbsrc.ukri.org/documents/forward-look-for-uk-bioscience-pdf/

	Name	Project title
	David Kealy University of Leeds 2015	How does the human papillomavirus (HPV) E5 protein control skin cell growth and differentiation during a productive life cycle?
	Nicholas Hurst University of Leeds 2015	Molecular basis for specific regulation of the stress sensor IRE1 in cancer cells
	James Horne University of Leeds 2015	Chaperone-assisted protein folding in the bacterial periplasm
	Francis Hopkins University of Leeds 2015	Structural Biology of RiboNucleoProtein complexes of pathogenic arena and bunyaviruses
	Sophie Hesketh University of Leeds 2015	Developing our structural understanding of the TRPM2 channel through electron microscopy studies
	Brittany Graham University of Leeds 2015	Muscle ageing and gene expression balance in Caenorhabditis elegans
	Jack Bravo University of Leeds 2015	Mechanism of Genomic Segment Assortment in Avian Reovirus
	Peter Fisher University of York 2014	Predicting glycan alterations in mammalian cells
	Emily Breardon University of Sheffield 2013	Discovery and functional analysis of Striga resistance genes in rice for targeted breeding of durable defence.
	Matthew Dooley University of Leeds 2014	Improving methods for the detection and monitoring of beetle pests through a deeper understanding of the mechanisms underlying beetle odour perception.
	Lia De Faveri University of Leeds 2014	Synthetic approaches to developing reagents for rapid, in-field detection of cereal rusts
	Emma Wroblewski University of Leeds 2014	Defining a novel assembly pathway in ssRNA viruses.
	Brendan Rogers University of Leeds 2014	The Structural Biology of the Z-disc in health and disease
	Grace Roberts University of Leeds 2014	Investigating the role of the nsP3 macro domain in Chikungunya virus replication
	Alistair Plant University of Leeds 2014	Co-Repression and the Evolution of Novel Plant Structures
	Ryan Kaye University of Leeds 2014	The Mechanisms of Gravity-Dependent Non-Vertical Growth in Higher Plants
	Alexander Coleman University of Leeds 2014	Virus remodelling of the nuclear pore complex : a novel antiviral target
	Lucy Barber University of Leeds 2014	New approaches to combatting amyloid disease from mechanistic insights
	Joseph Ward University of Leeds 2014	Understanding foot-and-mouth disease virus (FMDV) replication
	Samuel Bunce University of Leeds 2014	Developing Diazirines as Probes for Monitoring Dynamic Molecular Recognition Processes
	Simon Fairbanks University of Sheffield 2014	Structural studies on luminescent probes for quadruplex DNA
	Elanor Harrison University of Sheffield 2014	Studying the roles of epigenetics in therapeutic protein production
	Nicholas Barber University of Sheffield 2014	Multigene engineering of secretion by mammalian cell factories
	Rachel Denley-Bowers University of Sheffield 2014	The economics of stomatal distribution
	Jessica Dunn University of Sheffield 2014	The Effect of Manipulating Wheat Stomatal Development
	Mathew Parker University of Sheffield 2014	Deciphering microRNA networks using Next Generation Sequencing
	Jordan Talbot University of Sheffield 2014	A novel role for a specific chemokine in CNS function and disease
	Ben Aden Phillips University of Sheffield 2014	Investigating the mechanical regulation of autophagy
	Thomas Wilkinson University of York 2014	Plant-mediated interactions between above and below ground symbiotic microbes: implications for food security
	Michael King University of York 2014	Investigating the role of Capicua in mediating FGF transcriptional regulation in pluripotent stem cells
	Rachael Evans University of York 2014	Evolving microbial communities for biofuel production
	Samuel Dawes University of Sheffield 2014	NMR screening of small molecule inhibitors targeting endonuclease activity of an ER stress sensor Ire1
	Laura West University of York 2014	Structure-function studies of N1-Src kinase in axon guidance
	Cecilia Pennica University of York 2014	Probing the molecular interactions mediating the segregation of a multidrug resistance plasmid
	Caitlin McQueen University of York 2014	Turning on genes to build muscle
	Adam Hughes University of York 2014	Membrane Migration and Fission: Structure and Interaction of Proteins Mediating Phagocytosis during Sporulation in Bacillus subtilis
	Daniel Yee University of York 2014	Understanding cell-type specific regulation of microRNA biogenesis
	Banushan Balansethupathy University of York 2014	Evaluating the role of protein dynamics in double-stranded RNA recognition
	Thomas Hartley University of York 2013	Increasing the potassium use efficiency in crops
	Marc Cabry University of York 2013	Structural analysis of dioxygenases from opium poppy: towards the production of new biocatalytic tools for morphinan production
	Thomas Irving University of York 2013	How plants maintain a good relationship with beneficial fungi
	Elizabeth Hollwey University of Leeds 2013	Leeds - Generating epigenetic diversity in plants
	Hannah Southam University of Sheffield 2013	CO-releasing molecules as novel antimicrobial agents: mechanisms of transport and resistance
	Ian Bennet University of Sheffield 2013	Protein and DNA Dynamics in 5'-Nuclease Mechanistic Biology
	Bryony Cotterell University of Sheffield 2013	Bacterial Cell Wall Mapping at the Nanoscale
	Aidan Taylor University of Sheffield 2013	Understanding the resistance of pathogenic bacteria to host innate defences
	Elliot Jokl University of York 2013	Mechanotransduction through z-disc complexes of the skeletal muscle
	Grace Hoysted University of Leeds 2013	Plant-mediated interactions between above-and below-ground crop pests: molecular and biochemical mechanisms
	Nicole Jackson University of Leeds 2013	From inhibitor to antibacterial agent: delineating the physico-chemical properties required of small molecules to enable bacterial uptake
	Robert Thomas University of Leeds 2013	Computational modelling of growth angle control across the higher plants