PhD Projects

Our students are studying diverse areas of mechanistic biology in the following BBSRC strategic themes:

Advancing the frontiers of bioscience discovery:

1) Understanding the rules of life (formerly World Class Underpinning Bioscience)

2) Transformative technologies (formerly Exploiting New Ways of Working)

Tackling strategic challenges:

3) Bioscience for sustainable agriculture and food (formerly Agriculture and Food Security)

4) Bioscience for renewable resources and clean growth (formerly Industrial Biotechnology and Bioenergy)

These are the new BBSRC priority areas, taken from strategic document, “Forward look for UK Bioscience”, available on the BBSRC website:

https://bbsrc.ukri.org/documents/forward-look-for-uk-bioscience-pdf/

	Name	Project title
	James Forsythe University of York 2018	How does the circadian clock regulate disease resistance?
	Ashley Hayes University of Leeds 2018	Investigating How Nematodes Manipulate the Plant Secretory Pathway
	John Armstrong University of York 2017	Borrowing building blocks from bacteria and eukaryotes: a three-component DNA segregation machinery in archaea
	Rachael Cooper University of York 2017	How do repetitive bacterial surface proteins avoid inter-domain aggregation?
	Rhianna Rowland University of York 2017	Imaging agents for genetic disease: structural, chemical and cellular dissection
	Sarah Tindall University of York 2017	Structural analysis of acyltransferase proteins involved in O-antigen modification
	Sarah Thorne University of York 2017	Improved wheat yield with silicon
	Kirstin Spence University of York 2017	Investigating the molecular machinery that controls autophagy during Leishmania spp. Differentiation
	Edward Nay University of York 2017	Regulation of gene expression in Leishmania parasites: structure, function and post-transcriptional modification of RNA binding proteins
	Jessica Dobson University of York 2017	Mechanisms of palladium uptake and nanoparticle formation by plants
	Grace Dobbs University of York 2017	Role of CIZ1 in X chromosome inactivation
	Grace Cowen University of York 2017	Role of DNA methylation in brain function
	Ana Almeida Jones University of Sheffield 2017	Ahead of the curve: imaging and computational analysis of shape and form in the developing zebrafish ear
	Amy Tooke University of Sheffield 2017	Seeing is believing, observing bacterial biofilm formation in vivo
	Emily Guest University of Sheffield 2017	Linking metabolomics and metagenomics to resolve plant-microbial interactions involved in soil aggregation
	Amber Shun-Shion University of Sheffield 2017	Elucidating the role of STX19 in tissue morphogenesis using advanced bioimaging
	Ben Stevenson University of Sheffield 2017	The Dystroglycan LINC
	Ash Griffin University of Sheffield 2017	Application of high-resolution phosphoproteomics to reveal novel metabolic control mechanisms in Campylobacter jejuni
	Stella Christou University of Sheffield 2017	Elucidating the role of Endocytosis in Candida survival and proliferation in host cells
	Ben Scales University of Sheffield 2017	Neural bases of honeybee visual information processing and locomotion control
	Daniel Green University of Sheffield 2017	Neural circuit mechanisms of adaptation or sensitisation to neonicotinoid insecticides
	Lorna Malone University of Sheffield 2017	Structural role of photosystem II supercomplexes in thylakoid membrane stacking
	Shauni McGregor University of Sheffield 2017	The Mechanics of Stomatal Function
	Sarah Stevenson (nee Gratton) University of Sheffield 2017	Generating distinct actin networks in a single cytoplasm: Structural studies to determine the impact of actin nucleators on filament structure
	Ivaylo Yonchev University of Sheffield 2017	How does DNA damage alter nuclear mRNA export in humans?
	Ankur Patel University of Sheffield 2017	CASE - Development of an automated, high-resolution analysis pipeline for bacterial peptidoglycan structural analyses
	Laurence de Lussy-Kubisa University of Sheffield 2017	CASE - High-throughput genetic analysis of a butanol-producing Clostridia
	Thomas Grand University of Sheffield 2017	CASE - The Mechanism of Cell Cycle Repression in Tubers
	Alice Thomas University of York 2017	More Sustainable Crop Production by Using Better Fertilisers (CASE)
	Oliver Noble University of York 2017	MCMs: a novel nanopore (CASE)
	Maria Markham University of York 2017	CASE - Cell Stress and How to Prevent It
	Luke Trask University of Leeds 2017	CASE - Probing the functions of NEK family kinases using allosteric inhibitors
	Jonathan Dolan University of Leeds 2017	CASE - Orthogonal ligation strategies for making well defined glycoconjugate vaccines
	Bethan Cole University of Leeds 2017	CASE - Function and pharmacology of human Na+-activated K+ channels
	Jessica Boakes University of Leeds 2017	CASE - Structural characterisation of the equilibrative nucleoside transporter, a cancer drug target
	Jenny Hayes University of York 2016	CASE - Metabolic oligosaccharide engineering (MOE) using Sortases
	Nicola Burns University of York 2016	CASE - Genetic and environmental effects on virulence of European foulbrood, a bacterial pathogen of honey bees
	Patrick Shire University of Sheffield 2016	CASE - Mechanisms of endosomal permeability and release: a route for enhancing cytoplasmic delivery of endocytosed therapeutics
	Naomi Cox University of Sheffield 2016	CASE - Engineering the rice leaf for improved photosynthesis
	Oliver Carnell University of Sheffield 2016	CASE - Functional analysis of a novel, essential vaccine component of Staphylococcus aureus
	Rachel Taylor University of Leeds 2017	CASE - Characterization of WHIRLY1 functions in cereal crops
	Jess Ebo University of Leeds 2016	CASE - Evolving and improving protein stability for enhanced biopharmaceuticals
	Ioannis Tsagakis University of Leeds 2017	Dissecting the molecular mechanisms of lncRNA function in X chromosome inactivation across mammalian gestation evolution
	Danielle Pierce University of Leeds 2017	Understanding foot-and-mouth disease virus (FMDV) replication
	Jack Wright University of Leeds 2017	Structural and mechanistic insights into ABC transporters
	Hayley Pearson University of Leeds 2017	Understanding the Role of Cellular Chloride Channels in Virus Induced Cancers
	Adam Binns University of Leeds 2017	The molecular basis of primary root and shoot gravitropism
	Jumana Akhtar University of Leeds 2017	Nutrient impacts on plant secretions into soil
	Louise Richardson University of Leeds 2017	The Role of Satellite Cells in Skeletal Muscle Plasticity
	Holly Morgan University of Leeds 2017	Investigating enzymatic methods for preparation of protein conjugates