PIPS Opportunity: MetalloBio Antimicrobial Coating

MetalloBio is an antimicrobial development company working on completely novel types of antibacterial compounds. With two compound series, MetalloBio is developing Series 1 compounds as candidate antibiotics for complicated and difficult-to-treat infections. Series 2 compounds are the basis of new coatings for medical devices such as catheters and orthopaedic implants. Both series of compounds have novel but distinctly different modes of action in killing bacteria, reducing the risk of the emergence of resistant bacteria.

Project Overview

Healthcare-acquired infections represent a significant cost to the NHS, and increase the occupation of critical NHS bed space, whilst posing a lethal risk to patients. Infections are also among the top reasons for attending A&E with the most deprived communities of the UK having the highest rates of infection and A&E attendance, leading to higher rates of admissions and deaths compared to the rest of the population. To tackle this, MetalloBio is developing antimicrobial materials, that utilise the Series 2 compounds, to prevent and control the spread of infection in primary healthcare settings.

MetalloBio’s antimicrobial plastics have demonstrated activity against relevant bacteria at low loadings showing the potential for a more cost-effective performance than what is currently available. To fully understand the relevant product design requirements, MetalloBio utilises multiple sources of information, one of which is competitor products. Whether they are in development or clinically available, these products highlight what other companies or researchers deem as required. It will also involve conducting interviews with industry professionals through events such as trade shows.  Understanding the needs of this market helps to direct product development towards materials that compete with, or preferably perform better than, currently available products. MetalloBio will provide training enabling you to prepare for and conduct such primary research. Training will also be provided to enable you to confidently and clearly communicate with industry professionals during interviews and discussions.

Example project endpoints of the project could include a Pugh matrix that compares MetalloBio’s technology to currently available products and a product description that contributes to MetalloBio’s continued business justification.

Essential Skills

  • Ability to conduct methodical research
  • Experience conducting literature reviews
  • Communication and presentation skills
  • Ability to disseminate complex scientific research to a non-scientific audience

Skills Developed

  • Independent working & working as part of a small team
  • Competitor analysis and insights
  • Product development
  • Interview skills
  • Working under Prince2 Project Management
  • Understanding regulatory aspects of medical device development
  • Presenting a business case

Possible Timeframe

3 months part time with flexibility to start from September.

Application Process

To apply please email CV and short cover letter to matthew.culbert@metallobio.com.