Aidan Taylor

Understanding the resistance of pathogenic bacteria to host innate defences

Bacterial pathogens must resist host innate defences upon infection, but how they do this is not completely understood. We have recently discovered a previously unknown type of bacterial resistance mechanism against components of the innate immune system. This exciting project will investigate the structure and function of this system in a range of human pathogenic bacteria by an interdisciplinary approach involving molecular microbiology, protein biochemistry and structural biology.