Research Projects

2015-16

Here is list of the DTP’s Fourth cohort of students who began their projects in 2015.
Click on the project titles to find out more about the student.

Institution First name Surname Project title
Leeds Jack Bravo Mechanism of Genomic Segment Assortment in Avian Reovirus
Leeds Hannah Craven Cellular interactions with amyloid fibrils: cytotoxicity and protective mechanisms
Leeds Brittany Graham Muscle ageing and gene expression balance in Caenorhabditis elegans
Leeds Sophie Hesketh Determining how cargo binding regulates the activity of members of the kinesin3 family
Leeds Francis Hopkins Structural Biology of RiboNucleoProtein complexes of pathogenic arena and bunyaviruses
Leeds James Horne Chaperone-assisted protein folding in the bacterial periplasm
Leeds Nicholas Hurst Molecular basis for specific regulation of the stress sensor IRE1 in cancer cells
Leeds David Kealy How does the human papillomavirus (HPV) E5 protein control skin cell growth and differentiation during a productive life cycle?
Leeds Catherine Kendall Analysis and inhibition of chikungunya virus replication
Leeds Jaskiran Sabharwal Is the capture of RNA by RNase E and not its cleavage the major initiator of mRNA turnover
Leeds Anna Stikane Advancing Biotechnologies for Fuel Generation: Exploiting Transmembrane Cytochromes for Solar Energy Conversion
Leeds Katie Ward Mechanistic understanding of wheat productivity in relation to water supply using real-time moisture sensors and models
Sheffield David Farmer Nanodissection of protein-protein interactions in energy transducing membrane protein complexes
Sheffield Milena von und zur Muhlen Bacterial “presisters” – Antibiotic tolerance in action
Sheffield Harriet Knafler Investigating the role of endocytosis in the virulence of Candida albicans
Sheffield Eleanor Healicon The Mechanics of Shape Change in Plants
Sheffield Rebecca Ley Mechanistic Biology of Human Exonuclease-1-a DNA repair nuclease
Sheffield Christopher Banyard Investigation of a regulatory iron-sulfur complex in a bacterial sigma factor
Sheffield James Bradley Discovery and analysis of effector genes in the parasitic weed S. asiatica; a multi-faceted genomics approach
Sheffield Peter Bancroft Mycobacterium bovis aconitase-IRE interactions: integrating iron, oxidative and nitrosative stress responses
Sheffield Thomas Puttick Global control of enzyme activity in the food-borne human pathogen Campylobacter jejuni: Application of high-resolution mass spectrometry to reveal novel post-translational modifications
Sheffield Julia Morris The roles of a poorly characterized protease in rescuing the genome from protein linked DNA breaks
Sheffield Samir Morsli Innovative microscopy approaches to studying cellular senescence and regeneration in vivo
Sheffield Elisabeth Parker The role of AMF in drought alleviation in crops: identifying the underpinning physiological mechanisms
York Tobias Cracknell Revealing IGFN1 functional roles through in vivo CRISPR/CAS targeting and in vitro mechanical protein unfolding
York Rebecca Hall The microbiome of the tsetse
York Alexander Haworth Proteolytic processing of sodium channel ß1 subunits
York Nathaniel Holman Protein 0-glycosylation enzymes as targets for novel antimicrobials against mycobacteria
York Alexandra Males Chemical disruption of the 0-GlcNAc modification in the context of neurodengeration
York Caroline Pearson The biological role and structure functio analyses of 0-antigen modifying enzymes in the bacterial pathogen Salmonella
York Megan Sorensen Metabolic mechanisms of (photo)synthetic symbiosis
York Emma Stewart Nuclear matrix support of DNA replication and transcription
York Philip  Brailey Can soil microbial diversity mitigate water stress and maintain crop yield in agricultural systems?